Glutathione Considered – The Body’s Master Antioxidant

Posted by admin November 22nd, 2009

Antioxidants are intimately involved in the detoxification process and are a very important part of our defenses against environmental toxins and carcinogens. They protect our cells from oxidative stress which can come from our environment in a variety of ways. Because such damage plays a role in the weakening of the immune system that it should come as no surprise that antioxidant supplementation can benefit those with degenerative diseases such cardiovascular disease, cancer, arthritis, neurological diseases and viral infections for example.

Let’s look at one antioxidant –Glutathione- and how glutathione can affect the body. Glutathione is a small molecule made up of three amino acids, which exists in almost every cell of the body. The presence of glutathione is required to maintain the normal function of the immune system. It is known to play a critical role in the multiplication of lymphocytes (the cells that mediate specific immunity), which occurs in the development of an effective immune response. The cells of the immune system produce many oxygen radicals as a result of their normal functioning, resulting in a need for higher concentrations of antioxidants than most cells. Glutathione plays a crucial role in fulfilling this requirement.

Glutathione helps the body fight almost any disease, because it is a powerful antioxidant and helps maintain cellular health and there is a body of research on degenerative disease that has shown that people with degenerative disease are also experiencing low levels of glutathione. Glutathione acts as a detoxifying agent by combining with undesirable substances and ridding the body of them through urine and bile. Aside from being a powerful antioxidant and system detoxifier, it helps repair and protect DNA. Glutathione has been heavily researched and many researchers believe that the degenerative processes take place when the body is lacking the glutathione it needs to protect from degenerative damage.

Glutathione works in a protective role by boosting the immune system, thereby helping the body’s immune response and helps protect the body from oxidative stress – and oxidative stress is associated with aging. Thus, glutathione levels are correlated with aging and physical function. One way to drastically increase glutathione levels, aside from consuming glutathione precursors, is through the ingestion of ascorbic acid – vitamin C3 – and l-glutamine, vitamin E, ALA (Alpha Lipolic Acid), and N-acetylcysteine (NAC) which all help with glutathione synthesis.

Oxidation damage is now recognized as being the key feature of much of the aging processes that our bodies endure. It is known that as we age, there is a precipitous drop in GSH levels. Lower Glutathione levels are implicated in many diseases associated with aging, including Cataracts, Alzheimer’s disease, Parkinson’s, arteriosclerosis and others.

The key to living better is to resist age related deterioration due to oxidation. Recent studies have shown that glutathione play a key role in reducing the oxidation process (antioxidant) and protecting our bodies against free radicals. Supplements that increase glutathione may be a way for us to protect our bodies against the aging process.

What can reducing the oxidative process on the body mean for the athlete?

Many world-class athletes are discovering the importance of glutathione, which when maintained, gives them the edge over the competition. Increased glutathione levels provides athletes with increased strength and endurance, decreased recovery time from injury, less pain and fatigue and possibly an increase in muscle-promoting activities.

During workouts, athletes generate free radicals which in turn lead to muscle fatigue and poorer performance. Glutathione neutralizes these radicals and allows our bodies to recover faster. Recent research indicates that the body has a natural tendency toward many degenerative diseases and aging itself. Some believe how well the body can protect itself from damage and recover from oxidative damage can be determined by measuring the intracellular stores of Glutathione.

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