Posts Tagged ‘detoxification’

Decrease Oxidative Stress Naturally in Healthy Older Men and Women?

anti-aging, disease, Free Radicals, nutrition, Recovery - Repair | Posted by admin November 8th, 2013

Compared with young adults, older adults have significantly impaired capacities to resist oxidative damage when faced with acute stress such as ischemia/reperfusion. This impairment likely contributes to increased morbidity and mortality in older adults in response to acute trauma, infections, and the susceptibility to diseases such as atherosclerosis, cancer, diabetes, and Alzheimer’s disease.  Consumption of foods high in polyphenols, particularly anthocyanins, have been associated with improved health, but the mechanisms contributing to these salutary effects remain to be fully established.

A study tested the hypothesis that consumption of tart cherry juice containing high levels of anthocyanins improves the capacity of older adults to resist oxidative damage during acute oxidative stress. In a double-blind, placebo-controlled, crossover design, data suggests that consumption of tart cherry juice improves antioxidant defenses in vivo in older adults as shown by an increased capacity to constrain an oxidative challenge and reduced oxidative damage to nucleic acids.

Oxidative stress, defined as an imbalance between the rate of formation and the rate of clearance of reactive oxygen and nitrogen species (RONS), is thought to be a key mechanism in the aging process and in a variety of age-related chronic diseases, including atherosclerosis, cancer, diabetes, and Alzheimer’s disease.

Research has recently shown that healthy older adults have an impaired capacity to resist oxidative damage after exposure to an acute stress compared with young adults.  This impairment may account for the greater morbidity and mortality of older adults compared with young adults during trauma, infections, or surgery, as well as their increased susceptibility to cardiovascular and neurodegenerative disease.   Acute stress increases production of reactive oxygen species and frequently occurs in acute events that afflict older adults such as trauma, cardiovascular disease, and surgery.

The antioxidative capacity of older adults appears to be sufficient to maintain homeostasis in non-stressed conditions, but insufficient to cope with a substantial oxidative challenge. Therefore, identifying interventions that improve resistance to oxidative damage during an acute challenge might be of great potential value in decreasing morbidity and mortality in older adults, even if these interventions do not affect basal levels of oxidation.

It has been proposed that the antioxidant activities of fruits and vegetables come from the additive and synergistic effects of their phytonutrients and that isolated dietary supplements do not exhibit these same benefits.  Therefore, an intervention that would provide a natural blend of phytonutrients lead to Tart cherries which have high levels of antioxidants in the form of phenolic compounds and anthocyanins.  Diets rich in polyphenols, especially anthocyanins, have been shown to increase resistance to oxidation in research models.

Because anthocyanins can activate xenobiotic responses, including expression of a plethora of antioxidant response genes, it is hypothesized that increasing the dietary intake of diverse antioxidants, such as those contained in tart cherry juice, would increase resistance to oxidative damage after an acute stress, an effect that could potentially dramatically improve resistance to morbidity and mortality in older adults.

The conclusion of the data from a placebo-controlled, crossover study demonstrated that a dietary antioxidant intervention through consumption of tart cherry juice improves antioxidant defenses in vivo in older adults as shown by an increased capacity to resist oxidative damage after an acute stress and reduced oxidative damage to nucleic acids. The results also highlighted the observation that various markers of oxidative damage may reflect different mechanisms of resistance to oxidative damage.

 

References:   The Journal of Nutritionhttp://jn.nutrition.org
published online August 19, 2009; doi:10.3945/jn.109.111716
research study conducted –
Kronos Longevity Research Institute, Phoenix, AZ; 5Kronos Science Laboratory, Phoenix, AZ 85016; and Vanderbilt University School of Medicine, Nashville, TN 37232

Super Foods for Health

anti-aging, Free Radicals, nutrition, Recovery - Repair | Posted by admin May 17th, 2011
Your health is your wealth and it provides the infrastucture for maintaining strength and performance.  Everyone, especially athletes need to learn and understand the basics of optimal nutrition and how it is key to high performance and rapid recovery.  Muscles cells are injured and replaced constantly and optimal cell replications require optimal nutrients to be available at all times.  Superfoods are natural and they provide the fuel for health, strength and performance.  Learn to like them and make them part of your diet.
Cabbage
Absent from most American kitchens, this cruciferous vegetable is a major player in European and Asian diets.
Why It’s Healthy:
One cup of chopped cabbage has just 22 calories, and it’s loaded with valuable nutrients. At the top of the list is sulforaphane, a chemical that increases your body’s production of enzymes that disarm cell-damaging free radicals and reduce your risk of cancer. In fact, Stanford University scientists determined that sulforaphane boosts your levels of these cancer-fighting enzymes higher than any other plant chemical.
How to Eat It: Put cabbage on your burgers to add a satisfying crunch. Or, for an even better sandwich topping or side salad, try an Asian-style slaw. Here’s what you’ll need.
4 Tbsp peanut or canola oil
Juice of two limes
1 Tbsp sriracha, an Asian chili sauce you can find in the international section of your grocery store
1 head napa cabbage, finely chopped or shredded
1/4 cup toasted peanuts
1/2 cup shredded carrots
1/4 cup chopped cilantro
Whisk together the oil, lime juice, and sriracha. Combine the remaining ingredients in a large mixing bowl and toss with the dressing to coat. Refrigerate for 20 minutes before serving. The slaw will keep in your fridge for 2 days.
Beets
These grungy-looking roots are naturally sweeter than any other vegetable, which means they pack tons of flavor underneath their rugged exterior.
Why They’re Healthy: Think of beets as red spinach. Just like Popeye’s powerfood, this crimson vegetable is one of the best sources of both folate and betaine. These two nutrients work together to lower your blood levels of homocysteine, an inflammatory compound that can damage your arteries and increase your risk of heart disease. Plus, the natural pigments—called betacyanins—that give beets their color have been proved to be potent cancer fighters in laboratory mice.
How to Eat Them: Fresh and raw, not from a jar. Heating beets actually decreases their antioxidant power. For a simple single-serving salad, wash and peel one beet, and then grate it on the widest blade of a box grater. Toss with 1 tablespoon of olive oil and the juice of half a lemon. You can eat the leaves and stems, which are also packed with vitamins, minerals, and antioxidants. Simply cut off the stems just below the point where the leaves start, and wash thoroughly. They’re now ready to be used in a salad. Or, for a side dish, sauté the leaves, along with a minced clove of garlic and a tablespoon of olive oil, in a sauté pan over medium-high heat. Cook until the leaves are wilted and the stems are tender. Season with salt and pepper and a squeeze of lemon juice, and sprinkle with fresh Parmesan cheese.
Guava
Guava is an obscure tropical fruit that’s subtly acidic, with sweetness that intensifies as you eat your way to the center.
Why it’s Healthy: Guava has a higher concentration of lycopene—an antioxidant that fights prostate cancer—than any other plant food, including tomatoes and watermelon. In addition, 1 cup of the stuff provides 688 milligrams (mg) of potassium, which is 63 percent more than you’ll find in a medium banana. And guava may be the ultimate high-fiber food: There’s almost 9 grams (g) of fiber in every cup.
How to Eat It: Down the entire fruit, from the rind to the seeds. It’s all edible—and nutritious. The rind alone has more vitamin C than you’d find in the flesh of an orange. You can score guava in the produce section of higher-end supermarkets or in Latin grocery stores.
Swiss Chard
Hidden in the leafy-greens cooler of your market, you’ll find this slightly bitter, salty vegetable, which is actually native to the Mediterranean.
Why It’s Healthy: A half cup of cooked Swiss chard provides a huge amount of both lutein and zeaxanthin, supplying 10 mg each. These plant chemicals, known as carotenoids, protect your retinas from the damage of aging, according to Harvard researchers. That’s because both nutrients, which are actually pigments, appear to accumulate in your retinas, where they absorb the type of shortwave light rays that can damage your eyes. So the more lutein and zeaxanthin you eat, the better your internal eye protection will be.
How to Eat It: Chard goes great with grilled steaks and chicken, and it also works well as a bed for pan-seared fish. Wash and dry a bunch of Swiss chard, and then chop the leaves and stems into 1-inch pieces. Heat a tablespoon of olive oil in a large sauté pan or wok, and add two garlic cloves that you’ve peeled and lightly crushed. When the oil smokes lightly, add the chard. Sauté for 5 to 7 minutes, until the leaves wilt and the stems are tender. Remove the garlic cloves and season the chard with salt and pepper
Cinnamon
This old-world spice usually reaches most men’s stomachs only when it’s mixed with sugar and stuck to a roll.
Why It’s Healthy: Cinnamon helps control your blood sugar, which influences your risk of heart disease. In fact, USDA researchers found that people with type-2 diabetes who consumed 1 g of cinnamon a day for 6 weeks (about 1/4 teaspoon each day) significantly reduced not only their blood sugar but also their triglycerides and LDL (bad) cholesterol. Credit the spice’s active ingredients, methylhydroxychalcone polymers, which increase your cells’ ability to metabolize sugar by up to 20 times.
How to Eat It: You don’t need the fancy oils and extracts sold at vitamin stores; just sprinkle the stuff that’s in your spice rack (or in the shaker at Starbucks) into your coffee or on your oatmeal.
Purslane
Although the FDA classifies purslane as a broad-leaved weed, it’s a popular vegetable and herb in many other countries, including China, Mexico, and Greece.
Why It’s Healthy: Purslane has the highest amount of heart-healthy omega-3 fats of any edible plant, according to researchers at the University of Texas at San Antonio. The scientists also report that this herb has 10 to 20 times more melatonin—an antioxidant that may inhibit cancer growth—than any other fruit or vegetable tested.
How to Eat It: In a salad. Think of purslane as a great alternative or addition to lettuce: The leaves and stems are crisp, chewy, and succulent, and they have a mild lemony taste. Look for it at your local farmer’s market, or Chinese or Mexican market. It’s also available at some Whole Foods stores, as an individual leafy green or in premade salad mixes.
Pomegranate Juice
A popular drink for decades in the Middle East, pomegranate juice has become widely available only recently in the United States.
Why It’s Healthy: Israeli scientists discovered that men who downed just 2 ounces of pomegranate juice daily for a year decreased their systolic (top number) blood pressure by 21 percent and significantly improved bloodflow to their hearts. What’s more, 4 ounces provides 50 percent of your daily vitamin C needs.
How to Drink It:
Try 100 percent pomegranate juice from Pom Wonderful. It contains no added sugars, and because it’s so powerful, a small glassful is all you need. List of retailers, go to pomwonderful.com
Goji Berries
These raisin-size fruits are chewy and taste like a cross between a cranberry and a cherry. More important, these potent berries have been used as a medicinal food in Tibet for over 1,700 years.
Why They’re Healthy: Goji berries have one of the highest ORAC ratings—a method of gauging antioxidant power—of any fruit, according to Tufts University researchers. And although modern scientists began to study this ancient berry only recently, they’ve found that the sugars that make goji berries sweet reduce insulin resistance—a risk factor of diabetes—in rats.
How to Eat Them: Mix dried or fresh goji berries with a cup of plain yogurt, sprinkle them on your oatmeal or cold cereal, or enjoy a handful by themselves. Find them at specialty supermarkets or at gojiberries.us.
Dried Plums
You may know these better by the moniker “prunes,” which are indelibly linked with nursing homes and bathroom habits. And that explains why, in an effort to revive this delicious fruit’s image, producers now market them under another name.
Why They’re Healthy: Prunes contain high amounts of neochlorogenic and chlorogenic acids, antioxidants that are particularly effective at combating the “superoxide anion radical.” This nasty free radical causes structural damage to your cells, and such damage is thought to be one of the primary causes of cancer.
How to Eat Them: As an appetizer. Wrap a paper-thin slice of prosciutto around each dried plum and secure with a toothpick. Bake in a 400°F oven for 10 to 15 minutes, until the plums are soft and the prosciutto is crispy. Most of the fat will cook off, and you’ll be left with a decadent-tasting treat that’s sweet, savory, and healthy.
Pumpkin Seeds

These jack-o’-lantern waste products are the most nutritious part of the pumpkin.
Why They’re Healthy: Downing pumpkin seeds is the easiest way to consume more magnesium. That’s important because French researchers recently determined that men with the highest levels of magnesium in their blood have a 40 percent lower risk of early death than those with the lowest levels. And on average, men consume 353 mg of the mineral daily, well under the 420 mg minimum recommended by the USDA.

How to Eat Them: Whole, shells and all. (The shells provide extra fiber.) Roasted pumpkin seeds contain 150 mg of magnesium per ounce; add them to your regular diet and you’ll easily hit your daily target of 420 mg. Look for them in the snack or health-food section of your grocery store, next to the peanuts, almonds, and sunflower seeds.

Antioxidants, Explained
The science is clear:
Plant foods are good for you. And the credit often goes to chemicals they produce called antioxidants. Just as the name suggests, antioxidants help protect your cells against oxidation. Think of oxidation as rust. This rust is caused by free radicals, which are unstable oxygen atoms that attack your cells, inducing DNA damage that leads to cancer. Thankfully, antioxidants help stabilize free radicals, which keeps the rogue atoms from harming your cells. So by eating more antioxidant-rich foods, you’ll boost the amount of the disease-fighting chemicals floating in your bloodstream. The result: Every bite fortifies your body with all-natural preventive medicine.

 

Reference:  Men’s Health Magazine & Eat This? Not That!  – May 2011

Glutathione – Master Anti-Oxidant offers the Competitive Edge

anti-aging, Fitness, nutrition, performance, Recovery - Repair | Posted by admin August 30th, 2010

What is Glutathione?

Glutathione simply put is the “Master Antioxidant” in your body. Increasing glutathione levels will naturally increase your energy, detoxify your body and strengthen your immune system.

Research has shown that individuals that have low glutathione levels are susceptible to chronic illness including heart conditions, cancers, diabetes, seizures disorders, Alzheimer’s disease, and Parkinson’s disease to name a few. Our glutathione levels begin to decline at the age of 20 and do so at a rate of 8%-12% per decade.

Anti-Aging

Aging is the accumulation of changes in an organism overtime. Oxidation damage is now recognized as being the key feature of much of the aging processes that our bodies endure. The key to living better is to resist age related deterioration due to oxidation. Recent studies have shown that glutathione play a key role in reducing the oxidation process (antioxidant) and protecting our bodies against free radicals. Supplements that increase glutathione, may be a way for us to protect our bodies against the aging process.

Sports Enhancement

Many world-class athletes are discovering the importance of glutathione, which when maintained, gives them the edge over the competition. Increased glutathione levels provides athletes with increased strength and endurance, decreased recovery time from injury, less pain and fatigue and possibly an increase in muscle-promoting activities.

Athletes use glutathione for sports performance and recovery from their strenuous workouts. Up until very recently there was not a efficient way to get glutathione into our bodies other than intravenous (IV).

During workouts, athletes generate free radicals which in turn lead to muscle fatigue and poorer performance. Glutathione neutralizes these radicals and allows our bodies to recover faster.

Sports

Should Glutathione be a part of our exercise routine?

Free radicals are produced during normal cellular metabolism and increase when we exercise. These free radicals react within the cells by a process called oxidation and can result in inflammation to accumulate with our bodies. Overtime this inflammation accumulates within the cell and decreases the function of the cell and eventually leads to cellular death unless we have a way of reversing the process. To fight this cellular destruction our body uses an antioxidant, and the “Master Antioxidant” in the body is Glutathione.

Several studies have confirmed the beneficial effects of glutathione in protecting our bodies tissues from free radicals and exercise induced stress. Increasing Glutathione can increase energy, decrease recovery time and provide our cells with the tools so that they can function at an optimal level.

Ref: asktheRN.com

Bioavailable glutathione enhancement option link here:

Glutathione Considered – The Body’s Master Antioxidant

performance, Recovery - Repair | Posted by admin November 22nd, 2009

Antioxidants are intimately involved in the detoxification process and are a very important part of our defenses against environmental toxins and carcinogens. They protect our cells from oxidative stress which can come from our environment in a variety of ways. Because such damage plays a role in the weakening of the immune system that it should come as no surprise that antioxidant supplementation can benefit those with degenerative diseases such cardiovascular disease, cancer, arthritis, neurological diseases and viral infections for example.

Let’s look at one antioxidant –Glutathione- and how glutathione can affect the body. Glutathione is a small molecule made up of three amino acids, which exists in almost every cell of the body. The presence of glutathione is required to maintain the normal function of the immune system. It is known to play a critical role in the multiplication of lymphocytes (the cells that mediate specific immunity), which occurs in the development of an effective immune response. The cells of the immune system produce many oxygen radicals as a result of their normal functioning, resulting in a need for higher concentrations of antioxidants than most cells. Glutathione plays a crucial role in fulfilling this requirement.

Glutathione helps the body fight almost any disease, because it is a powerful antioxidant and helps maintain cellular health and there is a body of research on degenerative disease that has shown that people with degenerative disease are also experiencing low levels of glutathione. Glutathione acts as a detoxifying agent by combining with undesirable substances and ridding the body of them through urine and bile. Aside from being a powerful antioxidant and system detoxifier, it helps repair and protect DNA. Glutathione has been heavily researched and many researchers believe that the degenerative processes take place when the body is lacking the glutathione it needs to protect from degenerative damage.

Glutathione works in a protective role by boosting the immune system, thereby helping the body’s immune response and helps protect the body from oxidative stress – and oxidative stress is associated with aging. Thus, glutathione levels are correlated with aging and physical function. One way to drastically increase glutathione levels, aside from consuming glutathione precursors, is through the ingestion of ascorbic acid – vitamin C3 – and l-glutamine, vitamin E, ALA (Alpha Lipolic Acid), and N-acetylcysteine (NAC) which all help with glutathione synthesis.

Oxidation damage is now recognized as being the key feature of much of the aging processes that our bodies endure. It is known that as we age, there is a precipitous drop in GSH levels. Lower Glutathione levels are implicated in many diseases associated with aging, including Cataracts, Alzheimer’s disease, Parkinson’s, arteriosclerosis and others.

The key to living better is to resist age related deterioration due to oxidation. Recent studies have shown that glutathione play a key role in reducing the oxidation process (antioxidant) and protecting our bodies against free radicals. Supplements that increase glutathione may be a way for us to protect our bodies against the aging process.

What can reducing the oxidative process on the body mean for the athlete?

Many world-class athletes are discovering the importance of glutathione, which when maintained, gives them the edge over the competition. Increased glutathione levels provides athletes with increased strength and endurance, decreased recovery time from injury, less pain and fatigue and possibly an increase in muscle-promoting activities.

During workouts, athletes generate free radicals which in turn lead to muscle fatigue and poorer performance. Glutathione neutralizes these radicals and allows our bodies to recover faster. Recent research indicates that the body has a natural tendency toward many degenerative diseases and aging itself. Some believe how well the body can protect itself from damage and recover from oxidative damage can be determined by measuring the intracellular stores of Glutathione.

We support Prevention vs Prescriptions:
GoTo: Prevention not Prescriptions

Glutathione – Athletes Competitive Edge ?

performance, Recovery - Repair | Posted by admin August 26th, 2009

What is Glutathione?

Glutathione simply put is the “Master Antioxidant” in your body. Increasing glutathione levels will naturally increase your energy, detoxify your body and strengthen your immune system.

Research has shown that individuals that have low glutathione levels are susceptible to chronic illness including heart conditions, cancers, diabetes, seizures disorders, Alzheimer’s disease, and Parkinson’s disease to name a few. Our glutathione levels begin to decline at the age of 20 and do so at a rate of 8%-12% per decade.

Anti-Aging

Aging is the accumulation of changes in an organism overtime. Oxidation damage is now recognized as being the key feature of much of the aging processes that our bodies endure. The key to living better is to resist age related deterioration due to oxidation. Recent studies have shown that glutathione play a key role in reducing the oxidation process (antioxidant) and protecting our bodies against free radicals. Supplements that increase glutathione, may be a way for us to protect our bodies against the aging process.

Sports Enhancement

Many world-class athletes are discovering the importance of glutathione, which when maintained, gives them the edge over the competition. Increased glutathione levels provides athletes with increased strength and endurance, decreased recovery time from injury, less pain and fatigue and possibly an increase in muscle-promoting activities.

Athletes use glutathione for sports performance and recovery from their strenuous workouts. Up until very recently there was not a efficient way to get glutathione into our bodies other than intravenous (IV).

During workouts, athletes generate free radicals which in turn lead to muscle fatigue and poorer performance. Glutathione neutralizes these radicals and allows our bodies to recover faster.

Sports

Should Glutathione be a part of our exercise routine?

Free radicals are produced during normal cellular metabolism and increase when we exercise. These free radicals react within the cells by a process called oxidation and can result in inflammation to accumulate with our bodies. Overtime this inflammation accumulates within the cell and decreases the function of the cell and eventually leads to cellular death unless we have a way of reversing the process. To fight this cellular destruction our body uses an antioxidant, and the “Master Antioxidant” in the body is Glutathione.

Several studies have confirmed the beneficial effects of glutathione in protecting our bodies tissues from free radicals and exercise induced stress. Increasing Glutathione can increase energy, decrease recovery time and provide our cells with the tools so that they can function at an optimal level.

Ref: asktheRN.com

Bioavailable glutathione supplement option link here: