Posts Tagged ‘resistance’

Decrease Oxidative Stress Naturally in Healthy Older Men and Women?

anti-aging, disease, Free Radicals, nutrition, Recovery - Repair | Posted by admin November 8th, 2013

Compared with young adults, older adults have significantly impaired capacities to resist oxidative damage when faced with acute stress such as ischemia/reperfusion. This impairment likely contributes to increased morbidity and mortality in older adults in response to acute trauma, infections, and the susceptibility to diseases such as atherosclerosis, cancer, diabetes, and Alzheimer’s disease.  Consumption of foods high in polyphenols, particularly anthocyanins, have been associated with improved health, but the mechanisms contributing to these salutary effects remain to be fully established.

A study tested the hypothesis that consumption of tart cherry juice containing high levels of anthocyanins improves the capacity of older adults to resist oxidative damage during acute oxidative stress. In a double-blind, placebo-controlled, crossover design, data suggests that consumption of tart cherry juice improves antioxidant defenses in vivo in older adults as shown by an increased capacity to constrain an oxidative challenge and reduced oxidative damage to nucleic acids.

Oxidative stress, defined as an imbalance between the rate of formation and the rate of clearance of reactive oxygen and nitrogen species (RONS), is thought to be a key mechanism in the aging process and in a variety of age-related chronic diseases, including atherosclerosis, cancer, diabetes, and Alzheimer’s disease.

Research has recently shown that healthy older adults have an impaired capacity to resist oxidative damage after exposure to an acute stress compared with young adults.  This impairment may account for the greater morbidity and mortality of older adults compared with young adults during trauma, infections, or surgery, as well as their increased susceptibility to cardiovascular and neurodegenerative disease.   Acute stress increases production of reactive oxygen species and frequently occurs in acute events that afflict older adults such as trauma, cardiovascular disease, and surgery.

The antioxidative capacity of older adults appears to be sufficient to maintain homeostasis in non-stressed conditions, but insufficient to cope with a substantial oxidative challenge. Therefore, identifying interventions that improve resistance to oxidative damage during an acute challenge might be of great potential value in decreasing morbidity and mortality in older adults, even if these interventions do not affect basal levels of oxidation.

It has been proposed that the antioxidant activities of fruits and vegetables come from the additive and synergistic effects of their phytonutrients and that isolated dietary supplements do not exhibit these same benefits.  Therefore, an intervention that would provide a natural blend of phytonutrients lead to Tart cherries which have high levels of antioxidants in the form of phenolic compounds and anthocyanins.  Diets rich in polyphenols, especially anthocyanins, have been shown to increase resistance to oxidation in research models.

Because anthocyanins can activate xenobiotic responses, including expression of a plethora of antioxidant response genes, it is hypothesized that increasing the dietary intake of diverse antioxidants, such as those contained in tart cherry juice, would increase resistance to oxidative damage after an acute stress, an effect that could potentially dramatically improve resistance to morbidity and mortality in older adults.

The conclusion of the data from a placebo-controlled, crossover study demonstrated that a dietary antioxidant intervention through consumption of tart cherry juice improves antioxidant defenses in vivo in older adults as shown by an increased capacity to resist oxidative damage after an acute stress and reduced oxidative damage to nucleic acids. The results also highlighted the observation that various markers of oxidative damage may reflect different mechanisms of resistance to oxidative damage.

 

References:   The Journal of Nutritionhttp://jn.nutrition.org
published online August 19, 2009; doi:10.3945/jn.109.111716
research study conducted –
Kronos Longevity Research Institute, Phoenix, AZ; 5Kronos Science Laboratory, Phoenix, AZ 85016; and Vanderbilt University School of Medicine, Nashville, TN 37232

Super Foods for Health

anti-aging, Free Radicals, nutrition, Recovery - Repair | Posted by admin May 17th, 2011
Your health is your wealth and it provides the infrastucture for maintaining strength and performance.  Everyone, especially athletes need to learn and understand the basics of optimal nutrition and how it is key to high performance and rapid recovery.  Muscles cells are injured and replaced constantly and optimal cell replications require optimal nutrients to be available at all times.  Superfoods are natural and they provide the fuel for health, strength and performance.  Learn to like them and make them part of your diet.
Cabbage
Absent from most American kitchens, this cruciferous vegetable is a major player in European and Asian diets.
Why It’s Healthy:
One cup of chopped cabbage has just 22 calories, and it’s loaded with valuable nutrients. At the top of the list is sulforaphane, a chemical that increases your body’s production of enzymes that disarm cell-damaging free radicals and reduce your risk of cancer. In fact, Stanford University scientists determined that sulforaphane boosts your levels of these cancer-fighting enzymes higher than any other plant chemical.
How to Eat It: Put cabbage on your burgers to add a satisfying crunch. Or, for an even better sandwich topping or side salad, try an Asian-style slaw. Here’s what you’ll need.
4 Tbsp peanut or canola oil
Juice of two limes
1 Tbsp sriracha, an Asian chili sauce you can find in the international section of your grocery store
1 head napa cabbage, finely chopped or shredded
1/4 cup toasted peanuts
1/2 cup shredded carrots
1/4 cup chopped cilantro
Whisk together the oil, lime juice, and sriracha. Combine the remaining ingredients in a large mixing bowl and toss with the dressing to coat. Refrigerate for 20 minutes before serving. The slaw will keep in your fridge for 2 days.
Beets
These grungy-looking roots are naturally sweeter than any other vegetable, which means they pack tons of flavor underneath their rugged exterior.
Why They’re Healthy: Think of beets as red spinach. Just like Popeye’s powerfood, this crimson vegetable is one of the best sources of both folate and betaine. These two nutrients work together to lower your blood levels of homocysteine, an inflammatory compound that can damage your arteries and increase your risk of heart disease. Plus, the natural pigments—called betacyanins—that give beets their color have been proved to be potent cancer fighters in laboratory mice.
How to Eat Them: Fresh and raw, not from a jar. Heating beets actually decreases their antioxidant power. For a simple single-serving salad, wash and peel one beet, and then grate it on the widest blade of a box grater. Toss with 1 tablespoon of olive oil and the juice of half a lemon. You can eat the leaves and stems, which are also packed with vitamins, minerals, and antioxidants. Simply cut off the stems just below the point where the leaves start, and wash thoroughly. They’re now ready to be used in a salad. Or, for a side dish, sauté the leaves, along with a minced clove of garlic and a tablespoon of olive oil, in a sauté pan over medium-high heat. Cook until the leaves are wilted and the stems are tender. Season with salt and pepper and a squeeze of lemon juice, and sprinkle with fresh Parmesan cheese.
Guava
Guava is an obscure tropical fruit that’s subtly acidic, with sweetness that intensifies as you eat your way to the center.
Why it’s Healthy: Guava has a higher concentration of lycopene—an antioxidant that fights prostate cancer—than any other plant food, including tomatoes and watermelon. In addition, 1 cup of the stuff provides 688 milligrams (mg) of potassium, which is 63 percent more than you’ll find in a medium banana. And guava may be the ultimate high-fiber food: There’s almost 9 grams (g) of fiber in every cup.
How to Eat It: Down the entire fruit, from the rind to the seeds. It’s all edible—and nutritious. The rind alone has more vitamin C than you’d find in the flesh of an orange. You can score guava in the produce section of higher-end supermarkets or in Latin grocery stores.
Swiss Chard
Hidden in the leafy-greens cooler of your market, you’ll find this slightly bitter, salty vegetable, which is actually native to the Mediterranean.
Why It’s Healthy: A half cup of cooked Swiss chard provides a huge amount of both lutein and zeaxanthin, supplying 10 mg each. These plant chemicals, known as carotenoids, protect your retinas from the damage of aging, according to Harvard researchers. That’s because both nutrients, which are actually pigments, appear to accumulate in your retinas, where they absorb the type of shortwave light rays that can damage your eyes. So the more lutein and zeaxanthin you eat, the better your internal eye protection will be.
How to Eat It: Chard goes great with grilled steaks and chicken, and it also works well as a bed for pan-seared fish. Wash and dry a bunch of Swiss chard, and then chop the leaves and stems into 1-inch pieces. Heat a tablespoon of olive oil in a large sauté pan or wok, and add two garlic cloves that you’ve peeled and lightly crushed. When the oil smokes lightly, add the chard. Sauté for 5 to 7 minutes, until the leaves wilt and the stems are tender. Remove the garlic cloves and season the chard with salt and pepper
Cinnamon
This old-world spice usually reaches most men’s stomachs only when it’s mixed with sugar and stuck to a roll.
Why It’s Healthy: Cinnamon helps control your blood sugar, which influences your risk of heart disease. In fact, USDA researchers found that people with type-2 diabetes who consumed 1 g of cinnamon a day for 6 weeks (about 1/4 teaspoon each day) significantly reduced not only their blood sugar but also their triglycerides and LDL (bad) cholesterol. Credit the spice’s active ingredients, methylhydroxychalcone polymers, which increase your cells’ ability to metabolize sugar by up to 20 times.
How to Eat It: You don’t need the fancy oils and extracts sold at vitamin stores; just sprinkle the stuff that’s in your spice rack (or in the shaker at Starbucks) into your coffee or on your oatmeal.
Purslane
Although the FDA classifies purslane as a broad-leaved weed, it’s a popular vegetable and herb in many other countries, including China, Mexico, and Greece.
Why It’s Healthy: Purslane has the highest amount of heart-healthy omega-3 fats of any edible plant, according to researchers at the University of Texas at San Antonio. The scientists also report that this herb has 10 to 20 times more melatonin—an antioxidant that may inhibit cancer growth—than any other fruit or vegetable tested.
How to Eat It: In a salad. Think of purslane as a great alternative or addition to lettuce: The leaves and stems are crisp, chewy, and succulent, and they have a mild lemony taste. Look for it at your local farmer’s market, or Chinese or Mexican market. It’s also available at some Whole Foods stores, as an individual leafy green or in premade salad mixes.
Pomegranate Juice
A popular drink for decades in the Middle East, pomegranate juice has become widely available only recently in the United States.
Why It’s Healthy: Israeli scientists discovered that men who downed just 2 ounces of pomegranate juice daily for a year decreased their systolic (top number) blood pressure by 21 percent and significantly improved bloodflow to their hearts. What’s more, 4 ounces provides 50 percent of your daily vitamin C needs.
How to Drink It:
Try 100 percent pomegranate juice from Pom Wonderful. It contains no added sugars, and because it’s so powerful, a small glassful is all you need. List of retailers, go to pomwonderful.com
Goji Berries
These raisin-size fruits are chewy and taste like a cross between a cranberry and a cherry. More important, these potent berries have been used as a medicinal food in Tibet for over 1,700 years.
Why They’re Healthy: Goji berries have one of the highest ORAC ratings—a method of gauging antioxidant power—of any fruit, according to Tufts University researchers. And although modern scientists began to study this ancient berry only recently, they’ve found that the sugars that make goji berries sweet reduce insulin resistance—a risk factor of diabetes—in rats.
How to Eat Them: Mix dried or fresh goji berries with a cup of plain yogurt, sprinkle them on your oatmeal or cold cereal, or enjoy a handful by themselves. Find them at specialty supermarkets or at gojiberries.us.
Dried Plums
You may know these better by the moniker “prunes,” which are indelibly linked with nursing homes and bathroom habits. And that explains why, in an effort to revive this delicious fruit’s image, producers now market them under another name.
Why They’re Healthy: Prunes contain high amounts of neochlorogenic and chlorogenic acids, antioxidants that are particularly effective at combating the “superoxide anion radical.” This nasty free radical causes structural damage to your cells, and such damage is thought to be one of the primary causes of cancer.
How to Eat Them: As an appetizer. Wrap a paper-thin slice of prosciutto around each dried plum and secure with a toothpick. Bake in a 400°F oven for 10 to 15 minutes, until the plums are soft and the prosciutto is crispy. Most of the fat will cook off, and you’ll be left with a decadent-tasting treat that’s sweet, savory, and healthy.
Pumpkin Seeds

These jack-o’-lantern waste products are the most nutritious part of the pumpkin.
Why They’re Healthy: Downing pumpkin seeds is the easiest way to consume more magnesium. That’s important because French researchers recently determined that men with the highest levels of magnesium in their blood have a 40 percent lower risk of early death than those with the lowest levels. And on average, men consume 353 mg of the mineral daily, well under the 420 mg minimum recommended by the USDA.

How to Eat Them: Whole, shells and all. (The shells provide extra fiber.) Roasted pumpkin seeds contain 150 mg of magnesium per ounce; add them to your regular diet and you’ll easily hit your daily target of 420 mg. Look for them in the snack or health-food section of your grocery store, next to the peanuts, almonds, and sunflower seeds.

Antioxidants, Explained
The science is clear:
Plant foods are good for you. And the credit often goes to chemicals they produce called antioxidants. Just as the name suggests, antioxidants help protect your cells against oxidation. Think of oxidation as rust. This rust is caused by free radicals, which are unstable oxygen atoms that attack your cells, inducing DNA damage that leads to cancer. Thankfully, antioxidants help stabilize free radicals, which keeps the rogue atoms from harming your cells. So by eating more antioxidant-rich foods, you’ll boost the amount of the disease-fighting chemicals floating in your bloodstream. The result: Every bite fortifies your body with all-natural preventive medicine.

 

Reference:  Men’s Health Magazine & Eat This? Not That!  – May 2011

Protein Needs for Training . . .

nutrition | Posted by admin July 26th, 2009

Protein has been considered a key nutrient for sporting success by athletes of all eras and in all sports. Whereas ancient Olympians were reported to eat unusually large amounts of meat, today’s athletes are provided with a vast array of protein and amino acid supplements to increase their protein intakes.

Protein plays an important role in the response to exercise. Amino acids from proteins form building blocks for the manufacture of new tissue including muscle, and the repair of old tissue. They are also the building blocks for hormones and enzymes that regulate metabolism and other body functions. Protein provides a small source of fuel for the exercising muscle.

Some scientists have suggested that endurance and resistance-trained athletes in heavy training may have increased daily protein needs – up to a maximum of 1.2-1.7 g per kg body weight (BW), compared to the recommended intake of 0.8 g/kg BW for a sedentary person. However, the evidence for this increase in protein needs is not clear or universal. Part of the confusion is caused by problems involved in scientific techniques used to measure protein requirements. The debate over the precise protein needs of athletes is largely unnecessary.

Dietary surveys show that most athletes already consume diets providing protein intakes above the maximum recommended level, even without the use of protein supplements. Therefore, most athletes do not need to be encouraged or educated to increase their protein intakes. These surveys, however, relate mostly to athletes eating typical Western-style diets, and more information is urgently needed on athletes eating different food types.

Athletes most at risk of failing to meet their protein needs are those who severely restrict their energy intake or dietary variety. An adequate energy intake is important in promoting protein balance or increasing protein retention.

Although some resistance-trained athletes and body builders consume more than 2-3 g/kg BW, there is no evidence that these high daily protein intakes enhance the response to training or increase the gains in muscle mass and strength. Such diets are not necessarily harmful, but they are expensive and can fail to meet other nutritional goals, such as providing the fuel needed to optimize training and performance.

Recent studies have focused on the acute response to workouts of both endurance and resistance training. Enhanced protein balance is a desirable goal of the recovery phase – to overturn the increased rates of protein breakdown that occur during exercise, and to promote muscle growth, repair and adaptation following the exercise stimulus. These studies have found that eating a small amount of high-quality protein, combined with carbohydrate, enhances protein synthesis during the recovery period.

There is some evidence that the response is enhanced when these nutrients are provided soon after exercise, or in the case of a resistance workout, perhaps before training. Further work is required to fine-tune guidelines for the optimal amount, type and timing of intake of these nutrients, and to confirm that these eating strategies lead to an enhancement of the goals of training. In the light of this information, it appears sensible to focus on the total balance of the diet and the timing of protein-carbohydrate meals and snacks in relation to training, rather than on high protein intakes per se.

Special sports foods such as sports bars and liquid meal supplements can provide a compact and convenient way to consume carbohydrate and protein when everyday foods are unavailable or are too bulky and impractical to consume. However, the additional cost of these products, and the fact that they contain only a limited range of nutrients, must be taken into account. There is little justification for using very expensive protein-only powders or amino acid supplements. Everyday foods are likely to be just as effective.